Publications

Martin J Boulanger’s Citation Data (Google Scholar)

Martin J Boulanger’s Publications (PubMed)


2017


Parker ML, Ramaswamy R, van Gordon K, Powell C, Bosch J, Boulanger MJ. The
structure of Plasmodium falciparum 3D7_0606800 reveals a bi-lobed architecture
that supports re-annotation as a Venus Flytrap protein. Protein Sci. 2017 Jul 6.
doi: 10.1002/pro.3218.

Kelly FD, Wei BM, Cygan AM, Parker ML, Boulanger MJ, Boothroyd JC. Toxoplasma
gondii MAF1b Binds the Host Cell MIB Complex To Mediate Mitochondrial
Association. mSphere. 2017 May 24;2(3).


2016


Parker ML, Houston S, Wetherell C, Cameron CE, Boulanger MJ. The Structure of Treponema pallidum Tp0624 Reveals a Modular Assembly of Divergently Functionalized and Previously Uncharacterized Domains. PLoS One. 2016 Nov 10;11(11):e0166274.

Parker ML, Houston S, Pětrošová H, Lithgow KV, Hof R, Wetherell C, Kao WC, Lin YP, Moriarty TJ, Ebady R, Cameron CE, Boulanger MJ. The Structure of Treponema pallidum Tp0751 (Pallilysin) Reveals a Non-canonical Lipocalin Fold That Mediates Adhesion to Extracellular Matrix Components and Interactions with Host Cells. PLoS Pathog. 2016 Sep 28;12(9):e1005919.

Ramaswamy R, Goomeshi Nobary S, Eyford BA, Pearson TW, Boulanger MJ. Structural characterization reveals a novel bi-lobed architecture for the ectodomains of insect stage expressed Trypanosoma brucei PSSA-2 and Trypanosoma congolense ISA. Protein Sci. 2016 Sep 27.

Eyford BA, Kaufman L, Salama-Alber O, Loveless B, Pope ME, Burke RD, Matovu E, Boulanger MJ, Pearson TW. Characterization of Calflagin, a Flagellar Calcium-Binding Protein from Trypanosoma congolense. PLoS Negl Trop Dis. 2016 Apr 7;10(4):e0004510.

Adomako-Ankomah Y, English ED, Danielson JJ, Pernas LF, Parker ML, Boulanger MJ, Dubey JP, Boyle JP. Host mitochondrial association evolved in the human parasite Toxoplasma gondii via neofunctionalization of a gene duplicate. Genetics. 2016 May;203(1):283-98.

Delgadillo RF, Parker ML, Lebrun M, Boulanger MJ, Douguet D. Stability of the Plasmodium falciparum AMA1-RON2 complex is governed by the domain II (DII) loop. PLoS One. 2016 Jan 5;11(1):e0144764.

Parker ML, Penarete-Vargas DM, Hamilton PT, Guérin A, Dubey JP, Perlman SJ, Spano F, Lebrun M, Boulanger MJ. Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA-RON2 pair. Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):398-403.

Hamilton PT, Peng F, Boulanger MJ, Perlman SJ. A ribosome-inactivating protein in a Drosophila defensive symbiont. Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):350-5.


2015


Parker ML, Peng F, Boulanger MJ. The structure of Plasmodium falciparum blood-stage 6-Cys protein Pf41 reveals an unexpected intra-domain insertion required for Pf12 coordination. PLoS One. 2015 Sep 28;10(9):e0139407.

Parker ML, Boulanger MJ. An extended surface loop on Toxoplasma gondii Apical Membrane Antigen 1 (AMA1) governs ligand binding selectivity. PLoS One. 2015 May 8;10(5):e0126206.

Pihan E, Delgadillo RF, Tonkin ML, Pugnière M, Lebrun M, Boulanger MJ, Douguet D. Computational and biophysical approaches to protein-protein interaction inhibition of Plasmodium falciparum AMA1/RON2 complex. J Comput Aided Mol Des. 2015 Jun;29(6):525-39.

Blazejewski T, Nursimulu N, Pszenny V, Dangoudoubiyam S, Namasivayam S, Chiasson MA, Chessman K, Tonkin M, Swapna LS, Hung SS, Bridgers J, Ricklefs SM, Boulanger MJ, Dubey JP, Porcella SF, Kissinger JC, Howe DK, Grigg ME, Parkinson J. Systems-based analysis of the Sarcocystis neurona genome identifies pathways that contribute to a heteroxenous life cycle. MBio. 2015 Feb 10;6(1).

Tonkin ML, Boulanger MJ. The shear stress of host cell invasion: Exploring the role of biomolecular complexes. PLoS Pathog. 2015 Jan 28;11(1):e1004539.


2014


Witchell TD, Eshghi A, Nally JE, Hof R, Boulanger MJ, Wunder EA Jr, Ko AI, Haake DA, Cameron CE. Post-translational modification of LipL32 during Leptospira interrogans infection. PLoS Negl Trop Dis. 2014 Oct 30;8(10):e3280.

Tonkin ML, Halavaty AS, Ramaswamy R, Ruan J, Igarashi M, Ngô HM, Boulanger MJ. Structural and functional divergence of the aldolase fold in Toxoplasma gondii. J Mol Biol. 2015 Feb 27;427(4):840-52.

Huynh MH, Boulanger MJ, Carruthers VB. A conserved apicomplexan microneme protein contributes to Toxoplasma gondii invasion and virulence. Infect Immun. 2014 Oct;82(10):4358-68.

Srinivasan P, Ekanem E, Diouf A, Tonkin ML, Miura K, Boulanger MJ, Long CA, Narum DL, Miller LH. Immunization with a functional protein complex required for erythrocyte invasion protects against lethal malaria. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10311-6.

Lamarque MH, Roques M, Kong-Hap M, Tonkin ML, Rugarabamu G, Marq JB, Penarete-Vargas DM, Boulanger MJ, Soldati-Favre D, Lebrun M. Plasticity and redundancy among AMA-RON pairs ensure host cell entry of Toxoplasma parasites. Nat Commun. 2014 Jun 17;5:4098.

Tonkin ML, Beck JR, Bradley PJ, Boulanger MJ. The inner membrane complex sub-compartment proteins critical for replication of the apicomplexan parasite Toxoplasma gondii adopt a pleckstrin homology fold. J Biol Chem. 2014 May 16;289(20):13962-73.

Simhadri C, Daze KD, Douglas SF, Quon TT, Dev A, Gignac MC, Peng F, Heller M, Boulanger MJ, Wulff JE, Hof F. Chromodomain antagonists that target the polycomb-group methyllysine reader protein chromobox homolog 7 (CBX7). J Med Chem. 2014 Apr 10;57(7):2874-83.

Houston S, Russell S, Hof R, Roberts AK, Cullen P, Irvine K, Smith DS, Borchers CH, Tonkin ML, Boulanger MJ, Cameron CE. The multifunctional role of the pallilysin-associated Treponema pallidum protein, Tp0750, in promoting fibrinolysis and extracellular matrix component degradation. Mol Microbiol. 2014 Feb;91(3):618-34.


2013


Poukchanski A, Fritz HM, Tonkin ML, Treeck M, Boulanger MJ, Boothroyd JC. Toxoplasma gondii sporozoites invade host cells using two novel paralogues of RON2 and AMA1. PLoS One. 2013 Aug 5;8(8):e70637.

Von Kreudenstein TS, Escobar-Carbrera E, Lario PI, D’Angelo I, Brault K, Kelly J, Durocher Y, Baardsnes J, Woods RJ, Xie MH, Girod PA, Suits MD, Boulanger MJ, Poon DK, Ng GY, Dixit SB. Improving biophysical properties of a bispecific antibody scaffold to aid developability: Quality by molecular design. MAbs. 2013 Sep-Oct;5(5):646-54.

Tonkin ML, Arredondo SA, Loveless BC, Serpa JJ, Makepeace KA, Sundar N, Petrotchenko EV, Miller LH, Grigg ME, Boulanger MJ. Structural and biochemical characterization of Plasmodium falciparum 12 (Pf12) reveals a unique interdomain organization and the potential for an antiparallel arrangement with Pf41. J Biol Chem. 2013 May 3;288(18):12805-17.

Tonkin ML, Workman SD, Eyford BA, Loveless BC, Fudge JL, Pearson TW, Boulanger MJ. Purification, crystallization and X-ray diffraction analysis of Trypanosoma congolense insect-stage surface antigen (TcCISSA). Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Dec 1;68(Pt 12):1503-6.

Tonkin ML, Crawford J, Lebrun ML, Boulanger MJ. Babesia divergens and Neospora caninum apical membrane antigen 1 structures reveal selectivity and plasticity in apicomplexan parasite host cell invasion. Protein Sci. 2013 Jan;22(1):114-27.


2012


Wasmuth JD, Pszenny V, Haile S, Jansen EM, Gast AT, Sher A, Boyle JP, Boulanger MJ, Parkinson J, Grigg ME. Integrated bioinformatic and targeted deletion analyses of the SRS gene superfamily identify SRS29C as a negative regulator of Toxoplasma virulence. MBio. 2012 Nov 13;3(6).

Bains J, Wulff JE, Boulanger MJ. Investigating terephthalate biodegradation: Structural characterization of a putative decarboxylating cis-dihydrodiol dehydrogenase. J Mol Biol. 2012 Oct 26;423(3):284-93.

Tonkin ML, Brown S, Beck JR, Bradley PJ, Boulanger MJ. Purification, crystallization and preliminary X-ray diffraction analysis of inner membrane complex (IMC) subcompartment protein 1 (ISP1) from Toxoplasma gondii. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jul 1;68(Pt 7):832-4.

Murray JI, Tonkin ML, Whiting AL, Peng F, Farnell B, Cullen JT, Hof F, Boulanger MJ. Structural characterization of S100A15 reveals a novel zinc coordination site among S100 proteins and altered surface chemistry with functional implications for receptor binding. BMC Struct Biol. 2012 Jul 2;12:16.

Vulliez-Le Normand B, Tonkin ML, Lamarque MH, Langer S, Hoos S, Roques M, Saul FA, Faber BW, Bentley GA, Boulanger MJ, Lebrun M. Structural and functional insights into the malaria parasite moving junction complex. PLoS Pathog. 2012;8(6):e1002755.


2011


Bromba CM, Mason JW, Brant MG, Chan T, Lunke MD, Petric M, Boulanger MJ, Wulff JE. The de-guanidinylated derivative of peramivir remains a potent inhibitor of influenza neuraminidase. Bioorg Med Chem Lett. 2011 Dec 1;21(23):7137-41.

Tonkin ML, Roques M, Lamarque MH, Pugnière M, Douguet D, Crawford J, Lebrun M, Boulanger MJ. Host cell invasion by apicomplexan parasites: Insights from the co-structure of AMA1 with a RON2 peptide. Science. 2011 Jul 22;333(6041):463-7.

Bains J, Leon R, Temke KG, Boulanger MJ. Elucidating the reaction mechanism of the benzoate oxidation pathway encoded aldehyde dehydrogenase from Burkholderia xenovorans LB400. Protein Sci. 2011 Jun;20(6):1048-59.

Loveless BC, Mason JW, Sakurai T, Inoue N, Razavi M, Pearson TW, Boulanger MJ. Structural characterization and epitope mapping of the glutamic acid/alanine-rich protein from Trypanosoma congolense: Defining assembly on the parasite cell surface. J Biol Chem. 2011 Jun 10;286(23):20658-65.

Law A, Boulanger MJ. Defining a structural and kinetic rationale for paralogous copies of phenylacetate-CoA ligases from the cystic fibrosis pathogen Burkholderia cenocepacia J2315. J Biol Chem. 2011 Apr 29;286(17):15577-85.

Lamarque M, Besteiro S, Papoin J, Roques M, Vulliez-Le Normand B, Morlon-Guyot J, Dubremetz JF, Fauquenoy S, Tomavo S, Faber BW, Kocken CH, Thomas AW, Boulanger MJ, Bentley GA, Lebrun M. The RON2-AMA1 interaction is a critical step in moving junction-dependent invasion by apicomplexan parasites. PLoS Pathog. 2011 Feb 10;7(2):e1001276.

Bains J, Kaufman L, Farnell B, Boulanger MJ. A product analog bound form of 3-oxoadipate-enol-lactonase (PcaD) reveals a multifunctional role for the divergent cap domain. J Mol Biol. 2011 Mar 11;406(5):649-58.

Houston S, Hof R, Francescutti T, Hawkes A, Boulanger MJ, Cameron CE. Bifunctional role of the Treponema pallidum extracellular matrix binding adhesin Tp0751. Infect Immun. 2011 Mar;79(3):1386-98.

Morgan MR, Jazayeri M, Ramsay AG, Thomas GJ, Boulanger MJ, Hart IR, Marshall JF. Psoriasin (S100A7) associates with integrin β6 subunit and is required for αvβ6-dependent carcinoma cell invasion. Oncogene. 2011 Mar 24;30(12):1422-35.